Intra-Cytoplasmic Sperm Injection (ICSI) is one of the Assisted Reproduction Techniques (ART) applied in cases of severe male infertility characterized with considerable motility and sperm count reduction (up to the total spermatozoa absence from ejaculate). The technique is also applied in cases of high sperm count with morphological changes.
Besides the factors listed above, there are other indications to ICSI such as immunologic and idiopathic infertility as well as numerous IVF failures.
The first procedure of Intra-Cytoplasmic Sperm Injection was made at the end of the last century. Now it is performed by infertility clinics worldwide.
What is the main difference between ICSI and IVF? Extracorporeal fertilization is efficient only if there are enough spermatozoa with good morphological properties. ICSI is efficient even in case of few spermatozoa of good quality.
The embryologist selects a spermatozoon with the best morphological properties, immobilizes it and inserts into an egg cell cytoplasm with the help of a special needle. Further cultivation of embryos created with ICSI does not differ from that of embryos created with IVF.
The efficiency of the procedure depends on the embryologist’s professional skills.